A 20-year-old woman presented with a 4-year history of progressively intermittent pain and swelling of both knees. There was no history of trauma. A physical examination revealed swollen and tender knees with a limited range of flexion movement. Joint aspiration recovered hematic joint fluid. Plain radiographs appear normal, but magnetic resonance imaging (MRI) showed a joint effusion with synovial hyperplasia and hyposignal seen on both Tl-and T2-weighted images was consistent with the haemosiderin deposits on both of knees (Fig. 1). An open synovectomy of the left knee was carried out. Histological analysis revealed papillary hypervascular synovial tissue remained by chronic inflammatory infiltrate including foamy histiocytes, mononuclear cells, giant cells, with numerous deposits of haemosiderin (Fig. 2). This constellation of findings was consistent with a diagnosis of PVNS. She made a routine postoperative recovery. Two months later a total synovectomy of the right knee was performed and the histopathological findings were the same as those for the previously operated side.
展开▼
