SYNTHESIS OF N, N-DIALKYL PHOSPHORAMIDIC DICHLORIDE FROM DIALKYL AMINE AND PHOSPHORYL CHLORIDE USING BASIC ANION EXCHANGE POLYMER RESINS/BEADS

摘要

An efficient and operationally simple method is developed for the synthesis of N, N-dialkyl phosphoramidic dichloride from dialkyl amine and phosphoryl chloride using basic anion exchange polymer resins/beads. In the reaction, polymer resin, acts as a. scavenger for HCI produced as by-product and desired product is distilled under vacuum. Reaction afforded N, N-dialkyl phosphoramidic dichloride in 3-4 hours with excellent yields from corresponding dialkylamine and phosphoryl chloride.