~(15)N NMR SPECTROSCOPY OF ANNULATED △~2-PYRAZOLINES AND △~2-1,2,4-TRIAZOUNES

摘要

Enantiopure △~2-pyrazolines and △~2-1,2,4-triazolines fused to the 1,4-benzodiazepine moiety, as well as △~2-pyrazolines annulated to the 1,5-benzoxazocine moiety (racemic) or inserted in a bis-1,3-pyrazolophane skeleton (enantiopure) were investigated through ~(15)N NMR spectroscopy in natural abundance. Nitrogen chemical shifts were determined by (1D)-INEPT experiments, while proton-nitrogen scalar coupling were obtained through 2D-J-HMBC experiments.