EFFORTS TOWARD THE SYNTHESIS OF PSEUDOLARIC ACID A: INTRAMOLECULAR BROMOETHERIFICATION AS A MULTIPURPOSE SYNTHETIC TOOL

摘要

Regioselective double bond cleavage within 5, required for access to the trans-fused perhydroazulene framework of pseudolaric acid A (1), has been accomplished via a highly diastereoselective intramolecular bromoetherification process, the latter serving a dual role as a protecting group tactic.