REACTION OF 3-IODOCHROMONE WITH NUCLEOPHILES 2.REACTION WITH MERCAPROAZOLES

摘要

3-Iodochromone(1a)easily reacted with mercaptoazoles in the presence of potassium carbonate to give 3-azolylthiochromones in good yields. In the case of 2-mercaptobenzimidazole(2a)as a nucleophile,the benzimidazo[2,1,b]thiazole derivative (4a)was obtained as the major product along with 3-(1H-benzimidazol-2-ylthio)chromone(3a).The ratio of the two products was found to be affected by the electron density on the nitrogen atom in the benzimidazole ring.