SYNTHESIS AND ALKYLATION OF SODIUM 4-THIOXO-1,4-DIHYDROQUINOLINE-3-SULFINATE

摘要

Reaction of 4-chloro-3-quinolinesulfonyl chloride(1)with sodium hydrogen sulfide led to sodium 4-thioxo-1,4-dihydro-3-quinolinesulfinate(2).Compound 2 in reactions with alkyl halides was monoalkylated to sodium 4-alkylsulfanyl-3-quinolinesulfinate(3)or double alkylated directly to 4-alkylsulfanyl-3-alkanesulfonylquinolines(4).