One-Pot synthesis of tetra-Substituted imidazolies on silica gel under microwave irradiation

摘要

A new procedure for synthesis of tetra-substituted imidazoles was developed.A series of imidazole deirvativesincluding siz new compounds weresynthesized by this procedure via condensation of benzoin,aromatic aldehydr,amine and ammonium acetate in the presence of silica gel under solvent-free microwave irradiation.