SOLVENT-FREE REACTION USING PHOSPHONIUM SALTS :CHLORINATION OF HYDROXYHETEROAROMATICS AND DEHYDRATION OF PRIMARY AMIDES

摘要

Solvent-free chlorination of heteroaromatics using the phosphonium salt,prepared by reaction of triphenylphosphine with N-chlorosuccinimide,was accomplished by microwave-irradiation or heating to give the corresponding chloroheteroaromatics.Similarly,primary amides was converted into nitriles by this method.