Synthesis of Tris(2-pyridyl)phosphine from Red Phosphorus and 2-Bromopyridine in the CsF-NaOH-DMSO Superbasic System

摘要

Pyridylphosphines are widely used as polydentate chemolabile P,N ligands for the design of multipurpose metal-complex catalysts, highly reactive building blocks in organic synthesis , and precursors in the preparation of new pharmaceuticals. Among pyridylphosphines, tris(2-pyridyl)phosphine is of special interest as a tripodal ligand of chelating type due to the geminal arrangement of the nitrogen atoms with respect to the phosphorus atom. Metal complexes obtained from tris(2-pyridyl)phosphine are efficient catalysts for industrially important processes, such as alkene hydroformylation, ethylene polymerization, methoxycarbonylation of acetylenes , and diene synthesis.