Wnt/beta-catenin signaling: Turning the switch

Cadigan KM

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Wnt/beta-catenin signaling: Turning the switch

机译：Wnt / beta-catenin信号：拨动开关

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The regulation of many targets of the Wnt/beta-catenin signaling pathway is thought to occur through a transcriptional switch that is achieved by beta-catenin binding to TCF transcription factors. Recent work indicates that beta-catenin's intrinsic affinity for TCF is not sufficient for the switch to occur.

机译：Wnt /β-catenin信号传导途径的许多靶标的调节被认为是通过转录开关发生的，该开关由β-catenin与TCF转录因子结合而实现。最近的工作表明，β-catenin对TCF的固有亲和力不足以进行转换。

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《Developmental cell》 |2008年第3期|共2页
作者
Cadigan KM;
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正文语种 eng
中图分类普通生物学;
关键词
TRANSCRIPTION; PATHWAY;

机译：转录;途径;

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Wnt/beta-catenin signaling: Turning the switch

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