Correlated analysis and pathological study on insulin resistance and cardiovascular endocrine hormone in elderly hypertension patients

摘要

Aims: The correlated analysis and pathological study on insulin resistance and cardiovascular endocrinehormone in elderly hypertension patients was investigated by clinical observation and physical experiments in my hospital. Materials and methods: Randomly enrolled 300 subjects seen at hospital from January 2011 to January 2013, which included 150 hypertension patients and 150 non-hypertension of healthy people, while 150 cases of hypertension patients as the experimental group, 150 cases of healthy people without hypertension acts as the control group. The t-PA of serum (plasma), activity of PAI, ANP, IS, ET were determined in this 300 subjects, and it studied on the correlation and pathological effect between insulin resistance and cardiovascular endocrine hormone in elderly hypertension patients. Results: The levels of PAI, ANP, ET are apparently higher in hypertension patients than in healthy control group (p < 0.05), while the t-PA, IS are obviously lower in hypertensive patients than in healthy control group (p > 0.05). Conclusion: This study has shown that there is a significant correlation and pathological effect between insulin resistance and cardiovascular endocrine hormone in hypertensive patients, and which plays an important role in genesis and development of hypertension in elderly people.