Epidermal Expression of Filaggrin/Profilaggrin Is Decreased in Atopic Dermatitis: Reverse Association With Mast Cell Tryptase and IL-6 but Not With Clinical Severity

Ilves Tiina; Tiitu Virpi; Suttle Mireille-Maria; Saarinen Jari Vilho; Harvima Ilkka Tapani

首页> 外文期刊>Dermatitis: contact, atopic, occupational, drug : official journal of the American Contact Dermatitis Society, North American Contact Dermatitis Group >Epidermal Expression of Filaggrin/Profilaggrin Is Decreased in Atopic Dermatitis: Reverse Association With Mast Cell Tryptase and IL-6 but Not With Clinical Severity

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Epidermal Expression of Filaggrin/Profilaggrin Is Decreased in Atopic Dermatitis: Reverse Association With Mast Cell Tryptase and IL-6 but Not With Clinical Severity

机译：异位性皮炎中丝蛋白/原丝蛋白的表皮表达减少：与肥大细胞胰蛋白酶和IL-6的反向关联，但与临床严重程度无关

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Background A decrease in filaggrin expression contributes to the pathogenesis of atopic dermatitis (AD) and can be modified by inflammatory factors.

机译：背景丝聚蛋白表达的下降有助于特应性皮炎（AD）的发病机理，并可被炎性因子修饰。

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《Dermatitis: contact, atopic, occupational, drug : official journal of the American Contact Dermatitis Society, North American Contact Dermatitis Group》 |2015年第6期|共8页
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Ilves Tiina; Tiitu Virpi; Suttle Mireille-Maria; Saarinen Jari Vilho; Harvima Ilkka Tapani;
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正文语种 eng
中图分类皮肤病学与性病学;
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1. Epidermal Expression of Filaggrin/Profilaggrin Is Decreased in Atopic Dermatitis: Reverse Association With Mast Cell Tryptase and IL-6 but Not With Clinical Severity [J] . Ilves Tiina, Tiitu Virpi, Suttle Mireille-Maria, Dermatitis: contact, atopic, occupational, drug : official journal of the American Contact Dermatitis Society, North American Contact Dermatitis Group . 2015,第6期

机译：异位性皮炎中丝蛋白/原丝蛋白的表皮表达减少：与肥大细胞胰蛋白酶和IL-6的反向关联，但与临床严重程度无关
2. Serum mast cell tryptase is not a useful marker for disease severity in psoriasis or atopic dermatitis. [J] . Gerdes S, Kurrat W, Mrowietz U British Journal of Dermatology . 2009,第4期

机译：血清肥大细胞类胰蛋白酶不是牛皮癣或特应性皮炎中疾病严重程度的有用标记。
3. Does filaggrin expression correlate with severity of clinical signs in dogs with atopic dermatitis? [J] . Marsella Rosanna Veterinary Dermatology . 2013,第2期

机译：异位性皮炎犬中丝蛋白的表达与临床体征的严重程度是否相关？
4. Association Between Epidermal Caspase-3 Cleavage and Dermal Interferon-y Expressing Cells in Atopic Dermatitis [C] . D. Simon, R.LP. Lindberg, E. Kozlowski, Collegium Internationale Allergologicum . 2007

机译：表皮胱天冬酶-3裂解与表达特应性皮炎中表达细胞的表皮胱天蛋白酶-3之间的关系
5. Deficiency in a Putative Glutathione Transferase Produces Atopic Dermatitis with Mast Cell-mediated Histaminergic Itch [D] . Emrick, Joshua James. 2018

机译：假定的谷胱甘肽转移酶缺乏会产生肥大性皮肤炎，伴肥大细胞介导的组胺性瘙痒
6. Hydrogen water ameliorates the severity of atopic dermatitis-like lesions and decreases interleukin-1β interleukin-33 and mast cell infiltration in NC/Nga mice [O] . Takuya Kajisa, Takuji Yamaguchi, Ailing Hu, 2017

机译：氢水改善了特应性皮炎样病变的严重程度并降低了NC / Nga小鼠的白介素1β白介素33和肥大细胞浸润
7. Mutations in FLG , the gene‐coding profilaggrin/filaggrin, are associated with putative hay fever in patients with atopic dermatitis [O] . Satoko Minakawa, Yasushi Matsuzaki, Hideyuki Suwa, 2020

机译：FLG中的突变是基因编码素蛋白/呋喃吡林，与特应性皮炎患者的推定的花粉发烧有关

Epidermal Expression of Filaggrin/Profilaggrin Is Decreased in Atopic Dermatitis: Reverse Association With Mast Cell Tryptase and IL-6 but Not With Clinical Severity

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