Treatment of Acanthosis Nigricans of the Axillae Using a Long-Pulsed (5-msec) Alexandrite Laser.

摘要

Background. Acanthosis nigricans of the axillae is a common cutaneous disorder that is difficult to treat. Objective. The objective was to assess the efficacy and safety of a long-pulsed alexandrite laser (5 msec) in the treatment of acanthosis nigricans of the axillae. Methods. A single axilla was treated using the long-pulsed alexandrite laser. Ten sessions were required, at fluences of 16 to 23 J/cm(2) using either 10- or 12.5-mm spot sizes. The untreated axilla served as a control. Results. Greater than 95% clearance was achieved after seven sessions. There was no recurrence after 2 years. The untreated axilla was unchanged. Conclusions. The long-pulsed alexandrite laser can effectively and safely treat acanthosis nigricans of the axillae. ALAN ROSENBACH, MD, AND RAMIN RAM, BS HAVE INDICATED NO SIGNIFICANT INTEREST WITH COMMERCIAL SUPPORTERS.