A Facile Synthesis of Naphthyl-Quinolyl Ethanes and Chromenyl-Quinolyl Ethanes

摘要

The reaction of alkaline 2, 4-dihydroxyquinoline 1 and 1-tetralone 2 in 2% sodium hydroxide solution with vinyl acetate afforded a brown solid 3, which on treatment with phosphorous oxychloride yielded 2, 4-dichloro-3-[1'(1-chloro-naphth-2-yl)ethyl] quinoline (4). the same reaction of 1 and chromanone 7 with vinyl acetate afforded 2, 4-dichloro-3-[1'-(4-chloro-2-methyl-chromen-3-yl)ethyl]quinoline (9).