An efficient synthesis of l-thia-5-azaspiro[5.5]undec-2-ene and its recyclization to l,5-diazaspiro[5.5]undec-2-ene and/or Spiro-Thieno[2,3-d/] pyrimidin-4(lH)-one derivatives

摘要

An efficient and direct synthesis of l-thia-5-azaspiro[5.5]undec-2-ene is described, and the base-catalyzed recyclization of this compound was studied. The products have been characterized by elemental analyses, and IR, MS, lHNMR,and l3C NMR spectroscopy.