Tris-N-(N ',N ',N '',N ''-tetramethylguanidyl)phosphine oxide synthesis and reaction with acids

摘要

The phosphoryl compound (O:)P(TMG)(3) (TMG = N',N',N",N"-tetramethylguanidyl) (6) was synthesized during attempts to obtain the potentially very basic (but still unknown) compound P(TMG)3 (1). Its reaction with HCl resulted in the triply protonated species 7. The crystal structure of compound 7 was determined; it crystallizes as a bis-dichloromethane solvate. Each protonated nitrogen forms a hydrogen bond to one chloride. A series of protonation experiments was conducted in order to test the behaviour of 6 towards weak acids.