Botulinum toxin a after microvascular ALT flap in a patient with squamous cell carcinoma of the tongue [Einsatz von botulinum toxin a nach mikrovaskul?rem ALT-lappen bei einem patienten mit zungen- und mundbodenkarzinom]

摘要

We report the case of a 23-year-old man presenting with a cT4 cN1 M0 squamous cell carcinoma of the right tongue. After tumor resection and covering of the defect with a microvascular anterolateral thigh (ALT) flap, the patient showed distinct drooling without any substantial regression after anticholinergic therapy. For this reason 75 units of Botox? were injected into the submandibular and parotid glands. After the intraglandular injections, good reduction of saliva secretion was achieved. The treatment improved flap healing, aspiration and patient satisfaction. Injection of botulinum toxin A into the salivary glands is a sufficient therapy for postoperative hypersalivation.