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Model for End Stage Liver Disease score does not predict graft survival after living donor liver transplantation.

机译:终末期肝病评分模型无法预测活体供肝移植后的移植物存活率。

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BACKGROUND/AIMS: Although the Model End-Stage Liver Disease (MELD) score has been effective in the prediction of mortality in patients awaiting liver transplantation, its predictive value of survival after living donor liver transplantation (LDLT) needs further study. METHODOLOGY: We report our experience with 142 cases of LDLT, analyzing the impact of the MELD score on the graft survival after LDLT. RESULTS: Of 142 grafts, 18 failed during the observation period. One-, 3- and 5-year survival rates were 92%, 87% and 82%, respectively. Cox proportional hazard model revealed that MELD score did not predict graft survival (p=0.43, relative risk = 1.0). CONCLUSIONS: The present results may indicate that the preoperative MELD score was of little help for determining the indication of LDLT.
机译:背景/目的:尽管模型终末期肝病(MELD)评分已有效预测了等待肝移植的患者的死亡率,但其对活体供肝移植(LDLT)后存活的预测价值仍有待进一步研究。方法:我们报告了142例LDLT的经验,分析了MELD评分对LDLT后移植物存活的影响。结果:在142个移植物中,有18个在观察期内失败。一年,三年和五年生存率分别为92%,87%和82%。 Cox比例风险模型显示,MELD评分不能预测移植物的存活率(p = 0.43,相对危险度= 1.0)。结论:目前的结果可能表明术前MELD评分对确定LDLT的指征几乎没有帮助。

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