Clinical meaning of BRAF mutation in Korean patients with advanced colorectal cancer

Kim Bun; Park Soo Jung; Cheon Jae Hee; Kim Tae Il; Kim Won Ho; Hong Sung Pil

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Clinical meaning of BRAF mutation in Korean patients with advanced colorectal cancer

机译：BRAF突变在韩国晚期大肠癌患者中的临床意义

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AIM: To evaluate the clinicopathological features of colorectal cancer (CRC) with a v-Raf murine sarcoma viral oncogene homolog B1 (BRAF) mutation and its molecular interaction with microsatellite instability (MSI) and v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog (KRAS) in patients with advanced CRCs.

机译：目的：评估具有v-Raf鼠肉瘤病毒癌基因同源物B1（BRAF）突变的结直肠癌（CRC）的临床病理特征及其与微卫星不稳定性（MSI）和v-Ki-ras2 Kirsten大鼠肉瘤病毒癌基因同源物的分子相互作用晚期CRC的患者（KRAS）。

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《World journal of gastroenterology :》 |2014年第15期|共7页
作者
Kim Bun; Park Soo Jung; Cheon Jae Hee; Kim Tae Il; Kim Won Ho; Hong Sung Pil;
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正文语种 eng
中图分类消化系及腹部疾病;
关键词
BRAF; Colorectal cancer; Molecular features; Chemotherapy response; Prognosis;

机译：BRAF;大肠癌;分子特征;化学疗法反应;预后;

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专利

1. Clinical meaning of BRAF mutation in Korean patients with advanced colorectal cancer [J] . Kim Bun, Park Soo Jung, Cheon Jae Hee, World journal of gastroenterology : . 2014,第15期

机译：BRAF突变在韩国晚期大肠癌患者中的临床意义
2. Clinical significance of BRAF non-V600E mutations on the therapeutic effects of anti-EGFR monoclonal antibody treatment in patients with pretreated metastatic colorectal cancer: the Biomarker Research for anti-EGFR monoclonal Antibodies by Comprehensive Cancer genomics (BREAC) study [J] . Eiji Shinozaki, Takayuki Yoshino, Kentaro Yamazaki, British Journal of Cancer . 2017,第10期

机译： BRAF 非V600E突变对治疗的转移性结直肠癌患者抗EGFR单克隆抗体的治疗作用的临床意义：基于综合癌症基因组学（BREAC）的抗EGFR单克隆抗体的生物标志物研究研究
3. Not All BRAF-Mutant Metastatic Colorectal Cancers Are Identical: Distinct Clinical Consequences of (non-V600)BRAF Mutations [J] . Van Cutsem Eric, Dekervel Jeroen Journal of Clinical Oncology . 2017,第23期

机译：并非所有BRAF-突变转移性结肠直肠癌都是相同的：（非V600）BRAF突变的明显临床后果
4. Isolation of Circulating Tumor Cells from Patients with Metastatic Colorectal Cancer Using Label-Free Microfluidic Technology for Enumeration and Detection of KRAS, BRAF, PIK3CA Mutation [C] . Haiyan Emily Liu, Evelyn Kidess-Sigal, Melanie Triboulet, International Molecular Medicine Tri-Conference. . 2016

机译：使用无标记微流体技术分离转移性结肠直肠癌患者的循环肿瘤细胞进行募准和检测KRA，BRAF，PIK3CA突变
5. Glucose deprivation selects for KRAS and BRAF mutations in colorectal cancer. [D] . Yun, Jihye. 2009

机译：葡萄糖剥夺选择结直肠癌中的KRAS和BRAF突变。
6. Clinical meaning of BRAF mutation in Korean patients with advanced colorectal cancer [O] . Bun Kim, Soo Jung Park, Jae Hee Cheon, 2014

机译：BRAF突变在韩国晚期大肠癌患者中的临床意义
7. Comment on ‘Clinical significance of BRAF non-V600E mutations on the therapeutic effects of anti-EGFR monoclonal antibody treatment in patients with pretreated metastatic colorectal cancer: the Biomarker Research for anti-EGFR monoclonal Antibodies by Comprehensive Cancer genomics (BREAC) study’ [O] . Matthew Dankner, April A. N. Rose 2018

机译：评论对预处理转移性结直肠癌患者抗EGFR单克隆抗体治疗抗EGFR单克隆抗体治疗的临床意义：综合癌症基因组学（BREAC）研究对抗EGFR单克隆抗体的生物标志物研究'

Clinical meaning of BRAF mutation in Korean patients with advanced colorectal cancer

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