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World association for the advancement of veterinary parasitology (WAAVP) guideline for testing the efficacy of ectoparasiticides for fish

机译:世界兽医寄生虫病学促进协会(WAAVP)指南,用于测试杀寄生虫剂对鱼类的功效

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摘要

This guideline is intended to assist in the planning and execution of studies designed to assess the efficacy of ectoparasiticides for fish. It is the first ectoparasite-specific guideline to deal with studies set in the aquatic environment and therefore provides details for the maintenance of environmental standards for finfish. Information is included on a range of pre-clinical study designs as well as clinical studies in commercial/production sites, set within a regulatory framework. It provides information on the study animals, their welfare, husbandry and environmental requirements during the study. The most commonly pathogenic ectoparasites are presented with relevant points regarding life history, host challenge and numeric evaluation. Preparation and presentation of both topical and oral test treatments is provided, together with guidance on data collection and analysis. The guideline provides a quality standard for efficacy studies on finfish, which will assist researchers and regulatory authorities worldwide and contribute to the wider objective of harmonisation of procedures.
机译:本指南旨在协助计划和执行旨在评估杀寄生虫剂对鱼类功效的研究。这是处理水生环境研究的第一个特定于外寄生虫的指南,因此为维护有鳍鱼类的环境标准提供了详细信息。信息包括在监管框架内设置的一系列临床前研究设计以及商业/生产场所的临床研究。它提供有关研究动物,其福利,饲养和环境要求的信息。介绍了最常见的致病性外寄生物,并提供了有关生活史,寄主挑战和数值评估的相关要点。提供了局部和口服测试治疗的准备和介绍,以及有关数据收集和分析的指南。该指南提供了有鳍鱼类功效研究的质量标准,该标准将帮助全世界的研究人员和监管机构,并为实现程序统一这一更广泛的目标做出贡献。

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