Using LNA Flow-Fish to Quantitatively Monitor Viral Infections in Infected Cells and Test the Efficacy of Antiviral Medications

摘要

As described herein, locked nucleic acids are used with flow cytometric-fluorescence in situ hybridization (LNA flow-FISH) detection of viral RNA in infected cells. This technique represents a straightforward way to monitor viral infection in cells and can be used to measure efficacy of potential antiviral compounds.