Analytic validation of commercially available immunoassays for the measurement of serum cobalamin and folate concentrations in pigs

摘要

BackgroundCobalamin (vitamin B-12) and folate (vitamin B-9) are important for the amino acid metabolism and nucleic acid synthesis. Immunoassays for the measurement of both vitamins in serum are routinely used in people, cats, and dogs, serving as indicators for clinical disorders including cobalamin and/or folate deficiency, small intestinal dysbiosis, or inadequate dietary supply of these vitamins. The analysis of these analytes may also be clinically useful in pigs.