Fabrication of aptamer decorated dextran coated nano-graphene oxide for targeted drug delivery

摘要

In the current study, dextran (DEX) was covalently conjugated to the surface of nano-GO sheets, making stable biocompatible dextran coated GO (GO-DEX). The prepared GO-DEX was nontoxic to 4T1 mammary carcinoma cell line at concentrations up to 300 mu g/mL.