Asymmetric Epoxidation of α,β-Unsaturated Ketones over Heterogenized Ghiral Proline Diamide Complex Catalyst in the Solvent-Free Condition

摘要

Chiral copper proline diamide complex has been immobilized on surface of mesoporous silica. These heterogenized complex catalysts were examined as asymmetric catalysts for the epoxidation of α,β-unsaturated carbonyl compounds with hydrogen peroxide, tert-butyl hydroperoxide and urea hydroperoxide as the oxidants under solvent-free condition. Enantiomeric excesses of up to 84% can be achieved conveniently with a good conversion using these promising catalysts.