Neonatal alloimmunization: A rare case of multiple alloantibody formation in a patient with disseminated histoplasmosis

摘要

Neonatal alloimmunization is exceedingly rare and reported in only isolated case reports.1'3 Relative immunodeficiency of the neonatal state, as well as poor interactions between antigen-presenting cells and T lymphocytes, may be causative.4 The exact pathophysiologic mechanism, with additional costimulatory or contributory factors, is unknown.