Stimulated thyroglobulin and neck ultrasonography facilitates postsurgical radioactive iodine remnant ablation selection in patients with low-risk well-differentiated thyroid carcinoma

摘要

We read with great interest the article by Rosario et al. (1), which concluded that a stimulated thyroglobulin (Stim-Tg) < 1 ng/mL combined with neck ultrasonography can be used to obviate the need for radioactive iodine remnant ablation (RRA) after a total thyroidectomy in low-risk well-differentiated thyroid carcinoma (WDTC) patients who do not have anti-Tg antibody interference. Based upon their retrospective analysis of a cohort of patients with low-risk WDTC, the authors have rightly concluded that a Stim-Tg of < 1 ng/mL combined with negative high-resolution neck ultrasonography after a total thyroidectomy has a negative predictive value (NPV) for residual thyroid carcinoma of almost 100%.