Treatment-related acute myeloid leukemia in a chronic lymphocytic leukemia patient: role of fludarabine?

摘要

Chronic lymphocytic leukemia (CLL) is associated with a two-fold increased risk of developing a second malignant tumor, most commonly a skin cancer [Travis et al 1992; Velez et al. 2014]. CLL is also known to be associated with an increased frequency of second hematological malignancies [Hatoum et al. 2007].