Results from the Timing of Intervention in Acute Coronary Syndrome trial offer insight into acute coronary syndrome treatment

摘要

Preliminary results from the largest intervention management trial performed to date, have suggested that patients with acute coronary syndromes (ACS), who are treated with early invasive strategies,_gain-very little advantage over those who underwent a delayed but more invasive strategy. The Timing of Intervention in Acute Coronary Syndrome (TIMACS) trial identified one exception, this was the group of patients at high baseline risk of myocardial infarction (MI). These patients responded well to angiography within 24 h followed by percutaneous coronary intervention or coronary artery bypass graft, and a significant reduction in death and further recurrent MI and stroke at 6 months when compared with the delayed strategy was observed.