Post-operative paediatric analgesic doses may be too low to be effective

摘要

Children may be receiving inadequate pain relief after operatons, research conducted by pharmacists at the Queen's University of Belfast suggests. The researchers, led by Professor James McElnay, head of the university's school of pharmacy, analysed more than 1,000 blood samples from almost 500 children. They used an analytical technique called sparse data analysis to estimate the pharmacokinetics and pharmacodynamics of a range of drugs used in paediatric medicine. Beneficial and adverse effects experienced by the children were also monitored.