Blood pressure regulation in women - differences emerge when challenged by orthostasis

摘要

Orthostatic stress and postural transitions are present in day to day life, yet for many people, provide substantial challenges. Evidence continues to emerge that suggests young women regulate blood pressure differently from young men (Hart et al. 2012) and are traditionally more prone to orthostatic intolerance. Many studies attribute such differences to the vaso-active effects of sex hormones because the disparity between young men vs. women is much more striking than the difference between post-menopausal women vs. older men. However, the effect of sex hormones is still unclear because of the difficulty in accounting for within-subject day-to-day variations and between-subject differences in endogenous oestrogen.