In reference to An electron microscopic study--correlation of gastroesophageal reflux disease and laryngopharyngeal reflux.

摘要

In the July 2010 issue of Laryngoscope, authors Park et al. published their study titled "An Electron Microscopic Study-Correlation of Gastroesophageal Reflux Disease and Laryngopharyngeal Reflux." Although it is well known that both gastroesophageal reflux disease (GERD) and laryngopharyngeal reflux (LPR) occur because of tissue reactions in the lower esophagus (GERD) and the pharyngeal and laryngeal (LPR) areas from regurgitated gastric fluids, the similarities of these two disorders are otherwise quite different and do not correlate well. The authors have not related that the majority of GERD patients do not have LPR or other extraesophageal reflux (EER) disorders, and that only 20% to 30% of LPR patients have associated GERD. Also not mentioned is the fact that LPR patients are invariably upright refluxers as opposed to GERD patients who are more inclined to reflux in the supine position. GERD is a time-honored well-described clinical entity of heartburn and regurgitation, and LPR is a significant but much different EER disorder both in diagnostic and treatment modalities.