In reference to An electron microscopic study--correlation of gastroesophageal reflux disease and laryngopharyngeal reflux.

摘要

Dear Editor:We read with interest the study by Park et al. titled "An Electron Microscopic Study-Correlation of Gastro-esophageal Reflux Disease and Laryngopharyngeal Reflux" on transmission electron microscopy (TEM) assessment of the histological changes in gastroesopha-geal reflux disease (GERD) and laryngopharyngeal reflux (LPR). They showed that the intracellular spaces of the distal esophagus were significantly increased in LPR with or without GERD. They suggested a common pathogenesis but did not offer any possible explanation. There are a few comments we would like to share regarding the study.