Anamorelin in patients with non-small-cell lung cancer and cachexia (ROMANA 1 and ROMANA 2): results from two randomised, double-blind, phase 3 trials

Temel Jennifer S.; Abernethy Amy P.; Currow David C.; Friend John; Duus Elizabeth M.; Yan Ying; Fearon Kenneth C.

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Anamorelin in patients with non-small-cell lung cancer and cachexia (ROMANA 1 and ROMANA 2): results from two randomised, double-blind, phase 3 trials

机译：非小细胞肺癌和恶病质患者（ROMANA 1和ROMANA 2）中的Anamorelin：两项随机，双盲，3期临床试验的结果

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Background Patients with advanced cancer frequently experience anorexia and cachexia, which are associated with reduced food intake, altered body composition, and decreased functionality. We assessed anamorelin, a novel ghrelin-receptor agonist, on cachexia in patients with advanced non-small-cell lung cancer and cachexia.

机译：背景技术患有晚期癌症的患者经常会出现厌食和恶病质，这与食物摄入减少，身体成分改变和功能降低有关。我们评估了新型生长素释放肽受体激动剂Anamorelin对晚期非小细胞肺癌和恶病质患者恶病质的影响。

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《The lancet oncology》 |2016年第4期|共13页
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Temel Jennifer S.; Abernethy Amy P.; Currow David C.; Friend John; Duus Elizabeth M.; Yan Ying; Fearon Kenneth C.;
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正文语种 eng
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1. Anamorelin in patients with non-small-cell lung cancer and cachexia (ROMANA 1 and ROMANA 2): results from two randomised, double-blind, phase 3 trials [J] . Temel Jennifer S., Abernethy Amy P., Currow David C., The lancet oncology . 2016,第4期

机译：非小细胞肺癌和恶病质患者（ROMANA 1和ROMANA 2）中的Anamorelin：两项随机，双盲，3期临床试验的结果
2. EVALUATION OF ANOREXIA-CACHEXIA SYMPTOMS/CONCERNS FROM ROMANA 2, A PHASE III TRIAL OF ANAMORELIN IN NON-SMALL CELL LUNG CANCER PATIENTS WITH CACHEXIA. [J] . Brewer Cheryl, Abernethy Amy, Currow David, Oncology nursing forum . 2015,第2期

机译：从ROMANA 2中评估厌食症-Cachexia症状/担忧，这是非小细胞肺癌患者中阿那莫林的III期临床试验。
3. ROMANA 3: a phase 3 safety extension study of anamorelin in advanced non-small-cell lung cancer (NSCLC) patients with cachexia [J] . Currow D., Temel J. S., Abernethy A., Annals of oncology: official journal of the European Society for Medical Oncology . 2017,第8期

机译：罗马纳3：高级非小细胞肺癌（NSCLC）患者的Anamorin患者第3期安全延伸研究
4. The impact of the type of resection on survival in patients with N1 non-small-cell lung cancers [C] . Umit Aydogmus, Levent Cansever, Yasar Sonmezoglu, 21st international conference on screening for lung cancer . 2009

机译：切除类型对N1非小细胞肺癌患者生存的影响
5. A Phase II, Randomized, Double-Blind, Placebo-Controlled Trial of Fish Oil (Eicosapentaenoic Acid and Docosahexaenoic Acid) on Lung and Systemic Inflammation in Patients with Acute Lung Injury. [D] . Stapleton, Renee Doney. 2010

机译：鱼油（二十碳五烯酸和二十二碳六烯酸）对急性肺损伤患者的肺和全身炎症的II期，随机，双盲，安慰剂对照试验。
6. ROMANA 3: a phase 3 safety extension study of anamorelin in advanced non-small-cell lung cancer (NSCLC) patients with cachexia [O] . D. Currow, J. S. Temel, A. Abernethy, -1

机译：ROMANA 3：anamorelin在恶病质晚期非小细胞肺癌（NSCLC）患者中的3期安全性扩展研究
7. ROMANA 3: a phase 3 safety extension study of anamorelin in advanced non-small-cell lung cancer (NSCLC) patients with cachexia [O] . D. Currow, J.S. Temel, A. Abernethy, 2017

机译：罗马纳3：高级非小细胞肺癌（NSCLC）患者的Anamorin患者第3期安全延伸研究

Anamorelin in patients with non-small-cell lung cancer and cachexia (ROMANA 1 and ROMANA 2): results from two randomised, double-blind, phase 3 trials

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