Longterm Safety and Efficacy of Subcutaneous Tocilizumab Monotherapy: Results from the 2-year Open-label Extension of the MUSASHI Study

Ogata Atsushi; Amano Koichi; Dobashi Hiroaki; Inoo Masayuki; Ishii Tomonori; Kasama Tsuyoshi; Kawai Shinichi; Kawakami Atsushi; Koike Tatsuya; Miyahara Hisaaki; Miyamoto Toshiaki; Munakata Yasuhiko; Murasawa Akira; Nishimoto Norihiro; Ogawa Noriyoshi; Ojima Tomohiro; Sano Hajime; Shi Kenrin; Shono Eisuke; Suematsu Eiichi; Takahashi Hiroki; Tanaka Yoshiya; Tsukamoto Hiroshi; Nomura Akira

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Longterm Safety and Efficacy of Subcutaneous Tocilizumab Monotherapy: Results from the 2-year Open-label Extension of the MUSASHI Study

机译：皮下Tocilizumab单药疗法的长期安全性和有效性：MUSASHI研究2年开放标签扩展的结果

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Objective. To evaluate the longterm safety and efficacy of subcutaneous tocilizumab (TCZ-SC) as monotherapy in patients with rheumatoid arthritis (RA).

机译：目的。为了评估类风湿关节炎（RA）患者皮下注射托珠单抗（TCZ-SC）作为单一疗法的长期安全性和有效性。

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来源
《The Journal of rheumatology》 |2015年第5期|共11页
作者
Ogata Atsushi; Amano Koichi; Dobashi Hiroaki; Inoo Masayuki; Ishii Tomonori; Kasama Tsuyoshi; Kawai Shinichi; Kawakami Atsushi; Koike Tatsuya; Miyahara Hisaaki; Miyamoto Toshiaki; Munakata Yasuhiko; Murasawa Akira; Nishimoto Norihiro; Ogawa Noriyoshi; Ojima Tomohiro; Sano Hajime; Shi Kenrin; Shono Eisuke; Suematsu Eiichi; Takahashi Hiroki; Tanaka Yoshiya; Tsukamoto Hiroshi; Nomura Akira;
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正文语种 eng
中图分类免疫性疾病;
关键词
RHEUMATOID ARTHRITIS; HUMANIZED MONOCLONAL ANTIBODIES; SUBCUTANEOUS INJECTIONS; ADVERSE EVENTS;

机译：类风湿关节炎;人源化单克隆抗体;皮下注射;不良事件;

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1. Longterm Safety and Efficacy of Subcutaneous Tocilizumab Monotherapy: Results from the 2-year Open-label Extension of the MUSASHI Study [J] . Ogata Atsushi, Amano Koichi, Dobashi Hiroaki, The Journal of rheumatology . 2015,第5期

机译：皮下Tocilizumab单药疗法的长期安全性和有效性：MUSASHI研究2年开放标签扩展的结果
2. LONGTERM EFFICACY AND SAFETY OF INOTERSEN FOR HEREDITARY TRANSTHYRETIN AMYLOIDOSIS: NEURO-TTR OPEN-LABEL EXTENSION 2-YEAR UPDATE [J] . Brannagan Thomas, Cruz Marcia Waddington, Wang Annabel, Muscle and Nerve . 2019,第S1期

机译：遗传性Transtin淀粉样蛋白蛋白腺苷病的长期疗效和安全性：Neuro-TTR开放标签延长2年更新
3. Evidence for safety and efficacy of risedronate in men with osteoporosis over 4years of treatment: Results from the 2-year, open-label, extension study of a 2-year, randomized, double-blind, placebo-controlled study [J] . BoonenS., LorencR.S., WenderothD., Bone . 2012,第3期

机译：利塞膦酸盐治疗骨质疏松症患者4年以上的安全性和有效性的证据：一项为期2年，开放标签，扩展研究，为期2年，随机，双盲，安慰剂对照研究的结果
4. An open-label, multicenter, randomized,comparative, safety, efficacy, cycle control,and quality of life study of CTR 25, Alesse ,and Ortho Tri-Cyclen [C] . Victoria Davis, Brian Hauck, Sheila Dunn, World Congress on Fertility and Sterility . 2004

机译：开放标签，多中心，随机，比较，安全，疗效，循环控制和CTR 25，Alesse和Ortho Tri-Cyclen的生命研究
5. Safety and Efficacy of the Immunomodulatory Drug (IMiD) Lenalidomide in Patients with Lymphoma: Development of RU051417I - Phase I/II Open-Label Study of R-ICE (Rituximab-Ifosfamide-Carboplatin-Etoposide) with Lenalidomide [R2-ICE] in Patients with First-Relapse/Primary Refractory Diffuse Large B-Cell Lymphoma (DLBCL). [D] . Kasi, Pashtoon Murtaza. 2018

机译：免疫调节药物来那度胺在淋巴瘤患者中的安全性和有效性：RU051417I-R-ICE（利妥昔单抗-异环磷酰胺-卡铂-依托泊苷）与来那度胺[R2-ICE]的I / II期开放标签研究的进展初次复发/原发性难治性弥漫性大B细胞淋巴瘤（DLBCL）。
6. Extended report: Long-term safety and efficacy of tocilizumab an anti-IL-6 receptor monoclonal antibody in monotherapy in patients with rheumatoid arthritis (the STREAM study): evidence of safety and efficacy in a 5-year extension study [O] . N Nishimoto, N Miyasaka, K Yamamoto, -1

机译：扩展报告：类风湿关节炎患者单一疗法中抗IL-6受体单克隆抗体托珠单抗的长期安全性和有效性（STREAM研究）：一项为期5年的扩展研究的安全性和有效性证据
7. Longterm Safety and Efficacy of Subcutaneous Tocilizumab Monotherapy: Results from the 2-year Open-label Extension of the MUSASHI Study [O] . Atsushi Ogata, Koichi Amano, Hiroaki Dobashi, 2015

机译：皮下来的皮下杀氧质单药治疗的长期安全性和有效性：武丘研究的2年开放标签延伸的结果

Longterm Safety and Efficacy of Subcutaneous Tocilizumab Monotherapy: Results from the 2-year Open-label Extension of the MUSASHI Study

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