Care bundles in intensive care units - Authors' reply

摘要

We thank Samad Golzari and Ata Mahmoodpoor for their interest and critical reading of our study about reducing antibiotic resistance in intensive care units.Our study was focused on reduction of the overall risk of transmission of antimicrobial-resistant bacteria, thereby aiming to reduce all infections acquired in intensive care units associated with these bacteria, including pneumonia and catheter-related infections. The point we made about care bundles and other interventions was that preventive practices other than the interventions assessed did not change during the study period. It does not imply that best practices, such as using care bundles, were not applied in participating centres. All participating units actually used best care according to national guidelines.