Direct One-Pot Reductive Amination of Aldehydes with Nitroarenes in a Domino Fashion: Catalysis by Gum-Acacia-Stabilized Palladium Nanoparticles

摘要

This note describes the direct reductive amination ofcarbonyl compounds with nitroarenes using gum acacia-palladium nanoparticles, employing molecular hydrogen asthe reductant. This methodology is found to be applicableto both aliphatic and aromatic aldehydes and a wide rangeof nitroarenes. The operational simplicity and the mildreaction conditions add to the value of this method as apractical alternative to the reductive amination of carbonylcompounds.