Reductive Cross-amination between Aniline or Nitroarene Derivatives and Alkylamines Catalyzed by Polysilane-immobilized Metal Nanoparticles

摘要

Alkylamines, which are widely found in natural products or pharmaceutical compounds, are very valuable as they exhibit significant bioactivities.[1] Reducitve amination is one of the most reliable methods to approach alkylamines compared with other counterparts such as nucleophilic substitutions of alkyl halides with primary amines that sometimes suffers from over alkylation.