Arsenic Exposure May Be a Risk Factor for Alzheimer's Disease

摘要

To the Editor: Alzheimer's disease is a progressive neurodegenerative disease, manifested by cognitive and memory deficits that impair daily activities and cause a variety of psychiatric and behavioral disturbances. Many risk factors have been proposed, which, due to some cellular and subcellular mechanisms, finally lead to brain nerve apoptosis.In Alzheimer's disease, signs of inflammation of microglia and astroglia are present inside and outside amyloid deposits. It has been shown that there is a relationship between inflammation, reduction of neuronal functions, and deposition of amyloid. In addition, epidemiological studies have shown that anti-inflammatory drugs could reduce the risk of Alzheimer's disease.