Two cases of infantile linear immunoglobulin A/immunoglobulin G bullous dermatosis

摘要

Linear immunoglobulin (lg)A bullous dermatosis (LABD) is a rare disease characterized clinically by multiple bullae, typically grouped in the "cluster of jewels", histologically by subepidermal bullae and by linear distribution of IgA deposition along the basement membrane zone (BMZ).1 LABD is subdivided into two types: infantile and adult type.1 In addition, occasional cases of LABD show IgG autoanti-body targeted to the BMZ.2 This variant of LABD has been designated as linear IgA/IgG bullous dermatosis (LAGBD).2 We report two non-familial, non-kindred cases of infantile LAGBD seen by the same pediatrician within 3 months.