GENERAL METHODS FOR THE PREPARATION OF I,2,4,5-TETRAOXANES - KEY STRUCTURES FOR THE DEVELOPMENT OF PEROXIDIC ANTIMALARIAL AGENTS

A. O. Terentev; D. A. Borisov; I. A. Yaremenko

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GENERAL METHODS FOR THE PREPARATION OF I,2,4,5-TETRAOXANES - KEY STRUCTURES FOR THE DEVELOPMENT OF PEROXIDIC ANTIMALARIAL AGENTS

机译：制备I，2,4,5-四氧杂戊酮的通用方法-过氧化物类抗氧剂开发的关键结构

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General methods are presented for the preparation of symmetric and asymmetric 1 ,2,4,5-tetraoxanes,based on peroxidation of carbonyl compounds and their derivatives.

机译：提出了基于羰基化合物及其衍生物的过氧化制备对称和不对称的1,2,4,5-四恶烷的通用方法。

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《Chemistry of heterocyclic compounds》 |2012年第1期|共4页
作者
A. O. Terentev; D. A. Borisov; I. A. Yaremenko;
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正文语种 eng
中图分类杂环化合物;
关键词
gem-bishydroperoxides; cyclic peroxides; hydrogen peroxide; ketones; 1; 2; 4; 5-tetraoxanes; malaria;

机译：宝石双氢过氧化物;环状过氧化物;过氧化氢;酮;1;2;4;5-四恶烷;疟疾;

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1. GENERAL METHODS FOR THE PREPARATION OF I,2,4,5-TETRAOXANES - KEY STRUCTURES FOR THE DEVELOPMENT OF PEROXIDIC ANTIMALARIAL AGENTS [J] . A. O. Terentev, D. A. Borisov, I. A. Yaremenko Chemistry of heterocyclic compounds . 2012,第1期

机译：制备I，2,4,5-四氧杂戊酮的通用方法-过氧化物类抗氧剂开发的关键结构
2. GENERAL METHODS FOR THE PREPARATION OF I,2,4,5-TETRAOXANES - KEY STRUCTURES FOR THE DEVELOPMENT OF PEROXIDIC ANTIMALARIAL AGENTS [J] . A. O. Terentev, D. A. Borisov, I. A. Yaremenko Chemistry of heterocyclic compounds . 2012,第1期

机译：制备I，2,4,5-四氧杂戊酮的通用方法-过氧化物类抗氧剂开发的关键结构
3. Structure-activity relationships of the antimalarial agent artemisinin. 6. The development of predictive in vitro potency models using CoMFA and HQSAR methodologies. [J] . Avery MitchellA, Alvim-Gaston Maria, Rodrigues CarlosR, Journal of Medicinal Chemistry . 2002,第2期

机译：抗疟药青蒿素的构效关系。 6.使用CoMFA和HQSAR方法开发体外预测性效能模型。
4. Identification of Novel Falcipain-2 Inhibitors as Potential Antimalarial Agents through Structure-Based Virtual Screening [C] . Honglin Li, Rolf Hilgenfeld, Hualiang Jiang, ICMSI;International conference of molecular simulations and applied informatics technologies . 2010

机译：通过基于结构的虚拟筛选鉴定新型Falcipain-2抑制剂作为潜在的抗疟药
5. Development of enantioselective agents and heme-targeted antimalarials. [D] . Iwaniuk, Daniel P. 2011

机译：对映选择性药物和血红素靶向抗疟药的开发。
6. Comparative Antimalarial Activities of Six Pairs of 1245-Tetraoxanes (Peroxide Dimers) and 124578-Hexaoxonanes (Peroxide Trimers) [O] . Yuxiang Dong, Darren Creek, Jacques Chollet, 2007

机译：六对1245-四恶烷（过氧化物二聚体）和124578-六氧杂环丁烷（过氧化物三聚体）的比较抗疟活性
7. Comparative Antimalarial Activities of Six Pairs of 1,2,4,5-Tetraoxanes (Peroxide Dimers) and 1,2,4,5,7,8-Hexaoxonanes (Peroxide Trimers)▿ [O] . Dong, Yuxiang, Creek, Darren, Chollet, Jacques, 2007

机译：六对1,2,4,5-四恶烷（过氧化物二聚物）和1,2,4,5,7,8-六氧杂环丁烷（过氧化物三聚物）的比较抗疟活性▿

GENERAL METHODS FOR THE PREPARATION OF I,2,4,5-TETRAOXANES - KEY STRUCTURES FOR THE DEVELOPMENT OF PEROXIDIC ANTIMALARIAL AGENTS

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