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首页> 外文期刊>The International Journal of Advanced Manufacturing Technology >Enhancing the biocompatibility of Ti6Al4V implants by laser surface microtexturing: an in vitro study
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Enhancing the biocompatibility of Ti6Al4V implants by laser surface microtexturing: an in vitro study

机译:通过激光表面微织构增强Ti6Al4V植入物的生物相容性:一项体外研究

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摘要

The biocompatibility of an implant material depends on the bulk physical properties as well as on the surface properties. Titanium alloy Ti6Al4V is a very popular biological implant material for its bulk physical properties resembling those of natural bone. It is possible to modify the surface properties of Ti6Al4V by laser irradiation. In the current study, using continuous wave fibre laser, grooves of different depths and widths have been created by varying laser power and scan speed. Laser frequency and duty cycle were varied to alter the inside surface topographies of the microgrooves. The surface wettability and the protein adsorption on the surface were found to be dependent on the microtexture parameters. To understand the effect of this type of texturing on the cell behaviour, MG63 cells have been cultured on the sample surfaces, and the result was studied after 3 and 5 days of cell culture. Surface features dimensionally closer to the cell dimensions are able to positively affect the viability and spreading of MG63 cells, as seen from this study.
机译:植入物材料的生物相容性取决于整体物理性质以及表面性质。钛合金Ti6Al4V是一种非常流行的生物植入物材料,因为它具有类似于天然骨骼的大量物理特性。通过激光照射可以改变Ti6Al4V的表面性能。在当前的研究中,使用连续波光纤激光器,通过改变激光功率和扫描速度已经创建了不同深度和宽度的凹槽。改变激光频率和占空比以改变微槽的内表面形貌。发现表面润湿性和蛋白质在表面上的吸附取决于微织构参数。为了了解这种纹理化对细胞行为的影响,已在样品表面培养了MG63细胞,并在细胞培养3天和5天后研究了结果。从这项研究可以看出,尺寸更接近细胞尺寸的表面特征能够积极影响MG63细胞的活力和扩散。

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