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Risk factor profile for chronic non-communicable diseases: Results of a community-based study in Kerala, India

机译:慢性非传染性疾病的风险因素概况:印度喀拉拉邦一项基于社区的研究结果

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Background & objectives: Kerala State is a harbinger of what will happen in future to the rest of India in chronic non-communicable diseases (NCD). We assessed: (i) the burden of NCD risk factors; (ii) estimated the relations of behavioural risk factors to socio-demographic correlates, anthropometric risk factors with behavioural risk factors; (iii) evaluated if socio-demographic, behavioural and anthropometric risk factors predicted biochemical risk factors; and (iv) estimated awareness, treatment and adequacy of control of hypertension and diabetes, in Kerala state.Methods: A total of 7449 individuals (51% women) stratified by age group, sex and place of residence were selected and information on behavioural risk factors; tobacco use, diet, physical activity, alcohol use, measured anthropometry, blood pressure was collected. Fasting blood samples were analysed for blood glucose, total cholesterol, high density lipoprotein cholesterol and triglycerides in a sample subset. Using multiple logistic regression models the associations between socio-demographic and anthropometric variables with biochemical risk factors were estimated.Results: The burden of NCD risk factors was high in our sample. Prevalence of behavioural and each of the biochemical risk factors increased with age, adjusting for other factors including sex and the place of residence. The odds ratios relating anthropometric variables to biochemical variables were modest, suggesting that anthropometric variables may not be useful surrogates for biochemical risk factors for population screening purposes.Interpretation & conclusions: In this large study of community-based sample in Kerala, high burden of NCD risk factors was observed, comparable to that in the United States. These data may serve to propel multisectoral efforts to lower the community burden of NCD risk factors in India in general, and in Kerala, in particular.
机译:背景和目标:喀拉拉邦预示着印度未来将在慢性非传染性疾病(NCD)中发生的事情。我们评估:(i)非传染性疾病危险因素的负担; (ii)估算行为危险因素与社会人口统计学相关性,人体测量危险因素与行为危险因素之间的关系; (iii)评估社会人口统计学,行为和人体测量学危险因素是否预测了生化危险因素;方法:选择喀拉拉邦高血压和糖尿病患者的认识,治疗和控制的充分性。方法:选择了按年龄,性别和居住地分层的7449个人(51%为女性),并记录了行为风险信息因素;收集烟草使用,饮食,体育锻炼,酒精使用,人体测量学,血压。对空腹血液样本中的血糖,总胆固醇,高密度脂蛋白胆固醇和甘油三酸酯进行分析。使用多元逻辑回归模型估计了社会人口统计学和人体测量学变量与生化危险因素之间的关联。结果:我们样本中非传染性疾病危险因素的负担很高。行为和每个生化危险因素的发生率随着年龄的增长而增加,并根据其他因素(包括性别和居住地)进行了调整。人体测量学变量与生化变量相关的比值比适中,表明人体测量学变量可能不是用于人口筛查目的的生化危险因素的替代指标。观察到的危险因素与美国相当。这些数据可能有助于推动多部门努力,以降低整个印度,尤其是喀拉拉邦的非传染性疾病危险因素的社区负担。

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