Efficient synthesis of 3-substituted indazoles using Pd-catalyzed intramolecular amination reaction of N-tosylhydrazones

摘要

The efficient method for the preparation of 3-substituted indazoles was developed using the palladium catalyzed intra-molecular amination reaction of 2-bromophenyl hydrazone derivatives. Good functional group compatibility was observed under mild reaction conditions and various 3-substituted indazoles were obtained in moderate to excellent yield.