SYNTHESIS OF 8-OXO-7,8-DIHYDRO-6-O-METHYL-2'-DEOXYGUANOSINE AND ITS USE AS A PROBE TO STUDY DNA-BASE EXCISION BY MUTY ENZYME

Varaprasad CV.; Grollman AP.; Johnson F.; Bulychev N.

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SYNTHESIS OF 8-OXO-7,8-DIHYDRO-6-O-METHYL-2'-DEOXYGUANOSINE AND ITS USE AS A PROBE TO STUDY DNA-BASE EXCISION BY MUTY ENZYME

机译：8-OXO-7,8-二氢-6-O-甲基-2'-脱氧鸟嘌呤的合成及其作为研究多酶酶解DNA碱基的探针

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A 23mer oligomer containing 8-oxo-7,8-dihydro-6-O-methyl-2'-deoxyguanosine (1) has been synthesized from 2'-deoxyguanosine. The activity of MutY protein coward this and a related oligomer containing 8-methoxy-dG has been studied. [References: 11]

机译：由2′-脱氧鸟苷合成了含有8-氧代-7，8-二氢-6-O-甲基-2′-脱氧鸟苷（1）的23mer低聚物。已经研究了MutY蛋白的活性，以及与之相关的含有8-甲氧基-dG的寡聚物。 [参考：11]

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《Tetrahedron letters: The International Journal for the Rapid Publication of Preliminary Communications in Organic Chemistry》 |1996年第1期|共4页
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Varaprasad CV.; Grollman AP.; Johnson F.; Bulychev N.;
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1. SYNTHESIS OF 8-OXO-7,8-DIHYDRO-6-O-METHYL-2'-DEOXYGUANOSINE AND ITS USE AS A PROBE TO STUDY DNA-BASE EXCISION BY MUTY ENZYME [J] . Varaprasad CV., Grollman AP., Johnson F., Tetrahedron letters: The International Journal for the Rapid Publication of Preliminary Communications in Organic Chemistry . 1996,第1期

机译：8-OXO-7,8-二氢-6-O-甲基-2'-脱氧鸟嘌呤的合成及其作为研究多酶酶解DNA碱基的探针
2. Urinary analysis of 8-oxo-7,8-dihydroguanine and 8-oxo-7,8-dihydro-2'-deoxyguanosine by isotope-dilution LC-MS/MS with automated solid-phase extraction: Study of 8-oxo-7,8-dihydroguanine stability. [J] . Hu CW, Chao MR, Sie CH Free Radical Biology and Medicine: The Official Journal of the Oxygen Society . 2010,第1期

机译：同位素稀释LC-MS / MS自动固相萃取分析尿中的8-oxo-7,8-8，dihydroguanine和8-oxo-7,8-dihydro-2'-deoxyguanosine：8-oxo-7的研究，8-二氢鸟嘌呤稳定。
3. Nucleotide excision repair of oxidised genomic DNA is not a source of urinary 8-oxo-7,8-dihydro-2 '-deoxyguanosine [J] . Evans Mark D., Mistry Vilas, Singh Rajinder, Free Radical Biology and Medicine: The Official Journal of the Oxygen Society . 2016,第Null期

机译：氧化基因组DNA的核苷酸切除修复不是尿液中8-oxo-7,8-dihydro-2'-deoxyguanosine的来源
4. Synthesis of Small Peptides to Probe Oligomeric Enzyme Structure in Pyrimidine Biosynthesis [C] . Betsy Huang, Allesha Cutlip, Raneem AlKhatib American Peptide Symposium . 2011

机译：嘧啶生物合成中探针寡聚酶结构的小肽的合成
5. Crystallographic and biochemical studies of the nucleotide excision repair enzymes UvrB and UvrC, and the metabolically important enzyme xanthine dehydrogenase [D] . Truglio, James Jacob 2004

机译：核苷酸切除修复酶UvrB和UvrC以及代谢重要的酶黄嘌呤脱氢酶的晶体学和生化研究
6. Gas phase studies of substrates for the DNA mismatch repair enzyme MutY [O] . Anna Zhachkina Michelson, Aleksandr Rozenberg, Yuan Tian, -1

机译：对于DNa错配修复酶底物的气相研究mutY
7. An electrochemiluminescence biosensor for 8-oxo-7,8-dihydro-2 '-deoxyguanosine quantification and DNA repair enzyme activity analysis using a novel bifunctional probe [O] . Wu Yiping, Yang Xiqiang, Zhang Bintian, 2015

机译：一种电化学发光生物传感器，用于使用新型双功能探针对8-oxo-7,8-dihydro-2'-deoxyguanosine进行定量和DNA修复酶活性分析

SYNTHESIS OF 8-OXO-7,8-DIHYDRO-6-O-METHYL-2'-DEOXYGUANOSINE AND ITS USE AS A PROBE TO STUDY DNA-BASE EXCISION BY MUTY ENZYME

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