Diels-Alder cycloadditions of 3,5-dibromo-2-pyrone with cycloalkenyl silyl ethers for the synthesis of bicarbocycles

摘要

3,5-Dibromo-2-pyrone underwent facile Diels-Alder [4+2] cycloadditions with cycloalkenyl silyl ethers to provide a series of tricyclolactones,with good to excellent chemical yields and stereoselectivity.The resulting cycloadducts could be readily converted into the corresponding bicarbocycles upon selective debromination and reductive lactone ring opening reactions.