A GENERAL METHOD FOR THE SYNTHESIS OF THIOESTER RESIN LINKERS FOR USE IN THE SOLID PHASE SYNTHESIS OF PEPTIDE-ALPHA-THIOACIDS

Canne LE.; Kent SBH.; Walker SM.

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A GENERAL METHOD FOR THE SYNTHESIS OF THIOESTER RESIN LINKERS FOR USE IN THE SOLID PHASE SYNTHESIS OF PEPTIDE-ALPHA-THIOACIDS

机译：合成硫醚树脂接头的通用方法，用于固相合成肽-α-硫代酸

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A generalized procedure for the synthesis of thioester linkers for use in stepwise solid phase peptide synthesis is reported. The linkers are compatible with Boc chemistry and, upon cleavage in HF, generate peptide C-terminal thioacids. [References: 15]

机译：据报导了用于逐步固相肽合成的硫酯连接基合成的一般方法。接头与Boc化学相容，并且在HF中裂解后，会生成肽C末端硫代酸。 [参考：15]

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《Tetrahedron letters: The International Journal for the Rapid Publication of Preliminary Communications in Organic Chemistry》 |1995年第8期|共4页
作者
Canne LE.; Kent SBH.; Walker SM.;
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正文语种 eng
中图分类有机化学;
关键词
Chemical synthesis; Proteins; Protease; Segment;

机译：化学合成蛋白质蛋白酶段;

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1. A GENERAL METHOD FOR THE SYNTHESIS OF THIOESTER RESIN LINKERS FOR USE IN THE SOLID PHASE SYNTHESIS OF PEPTIDE-ALPHA-THIOACIDS [J] . Canne LE., Kent SBH., Walker SM. Tetrahedron letters: The International Journal for the Rapid Publication of Preliminary Communications in Organic Chemistry . 1995,第8期

机译：合成硫醚树脂接头的通用方法，用于固相合成肽-α-硫代酸
2. An Orthogonal Double-Linker Resin Facilitates the Efficient Solid-Phase Synthesis of Complex-Type N-Glycopeptide Thioesters Suitable for Native Chemical Ligation [J] . Stefano Mezzato, Manuela Schaffrath, Carlo Unverzagt Angewandte Chemie . 2005,第11期

机译：正交双接头树脂有助于适用于天然化学连接的复杂型N-糖肽硫酸酯的高效固相合成
3. An alternate preparation of thioester resin linkers for solid-phase synthesis of peptide C-terminal thioacids [J] . Goldstein Alex S., Gelb Michael H. Tetrahedron letters: The International Journal for the Rapid Publication of Preliminary Communications in Organic Chemistry . 2000,第16期

机译：硫酯树脂接头的另一种制备方法，用于固相合成肽C端硫代酸
4. THIOAMIDE SOLID-PHASE PEPTIDE SYNTHESIS T-SPPS: A NOVEL SYNTHESIS METHOD FOR PEPTIDE THIOESTERS [C] . Andreas Pech, Nicole Wehofsky, Dirk Wildemann the European Peptide Symposium . 2007

机译：硫胺固相肽合成T-SPP：一种新型肽硫代酯的合成方法
5. New linkers and strategies for solid phase organic synthesis and their application to natural products synthesis and libraries thereof. Solid phase synthesis of HPE, epothilones, sarcodictyins, zearalenone and vancomycin [D] . Winssinger, Nicolas 2000

机译：固相有机合成的新接头和策略及其在天然产物合成及其文库中的应用。 HPE，埃博霉素，石co素，玉米赤霉烯酮和万古霉素的固相合成
6. Solid Phase Synthesis of Peptidyl Thioacids Employing a 9-Fluorenylmethyl Thioester-Based Linker in Conjunction with Boc Chemistry [O] . David Crich, Kasinath Sana -1

机译：肽基硫代酸采用9-芴硫酯为基础的接头的固相合成中用Boc化学连词
7. Solid-phase synthesis of peptidyl thioacids employing a 9-fluorenylmethyl thioester-based linker in conjunction with Boc chemistry. [O] . Crich, David, Sana, Kasinath 2009

机译：结合Boc化学方法，使用基于9-芴基甲基硫代酯的接头，固相合成肽基硫代酸。

A GENERAL METHOD FOR THE SYNTHESIS OF THIOESTER RESIN LINKERS FOR USE IN THE SOLID PHASE SYNTHESIS OF PEPTIDE-ALPHA-THIOACIDS

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