A concise method for the functionalisation of ethanloamine #alpha# to nitrogen usign free radcal methodology

摘要

A method is described for the free radical functionalisation of ethanolamine at the carbon atom #alpha# to nitrogen.The key step of the methodology is a 1.5-hydrogen atom abstraction to produce an #alpha#-aminoalkyl radical at C-4 of a 1,3-oxazolidine.