Safety, tolerability, and self-rated effects of aripiprazole and ropinirole treatment for cocaine dependence: a pilot study.

摘要

To date, there is no pharmacological therapy with established efficacy for the treatment of cocaine dependence. Recent reviews indicated that pharmacological agents such as GABA agents (topiramate, tiagabine, baclofen, and vigabatrin) and agonist replacement agents (modafinil, disulfiram, and methylphenidate) seem to be promising in treatment of cocaine dependence, but evidences are still inconclusive.