Hepatitis E Virus Exposure is Increased in Pork Butchers from Burkina Faso

摘要

We conducted the first survey of zoonotic risk of Hepatitis E virus (REV) transmissions in Ouagadougou, Burkina Faso, through the direct contact with pork meat during professional activity. Anti-REV antibodies were more prevalent in pork butchers, 76% than in the general population, which was 47.8% in 2013 (odds ratio = 3.46, 95% CI = 2.85-4.21, P < 0.001). Among slaughter-aged swine, REV seroprevalence was of 80%, and REV RNA was detected in 1% of pork livers. Phylogenetic analysis pointed out HEV genotype 3. Thus, in addition to possible HEV contamination through the water source, as in endemic region, zoonotic transmissions of REV probably occur in west Africa.