C-phosphanylated sulfoximines: synthesis and applications in asymmetric allylic substitution reactions

摘要

Starting from cyclic sulfonimidates, a number of C-phosphanylated enantiomerically pure sulfoximines have been prepared either as such or in protected form. Two of them, 5a and epi-5a, have been used as ligands in palladium complex catalyzed allylic substitution reactions delivering the substitution product with up to 95% ee. (c) 2006 Elsevier Ltd. All rights reserved.